An AAV capsid reprogrammed to bind human transferrin receptor mediates brain-wide gene delivery
Most Cited Paper
in Virus-based gene therapy research
18 Months Post-Publication
Class of 2026
“An AAV capsid reprogrammed to bind human transferrin receptor mediates brain-wide gene delivery”
A research intelligence initiative by Pepkio
pri.pepkio.com/top-papers/virus-based-gene-therapy-research/2026/
Topics
AAV capsid · BI-hTFR1 · TfR1 · TfR1 · Blood-Brain Barrier · brain-wide gene delivery · transcytosis · human brain endothelial cells · Adeno-Associated Virus Serotype 9 · human TFRC knockin mice · Neurotropism · GBA1 gene · Gaucher disease · Parkinson's disease · glucocerebrosidase activity · cerebrospinal fluid · CNS gene therapy · receptor-mediated transport
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Virus-based gene therapy research Papers, Class of 2026. https://pri.pepkio.com/top-papers/virus-based-gene-therapy-research/2026. Accessed 2026-07-20. Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459