Systematic multi-trait AAV capsid engineering for efficient gene delivery
Most Cited Paper
in Virus-based gene therapy research
18 Months Post-Publication
Class of 2026
“Systematic multi-trait AAV capsid engineering for efficient gene delivery”
A research intelligence initiative by Pepkio
pri.pepkio.com/top-papers/virus-based-gene-therapy-research/2026/
Topics
Fit4Function · Capsid Engineering · machine learning models · sequence-to-function models · Peptide-Modified Capsid · liver-targeted capsids · manufacturability · cross-species prediction · macaque biodistribution · human hepatocyte transduction · capsid library design · uniform sequence space sampling · multi-trait optimization · Adeno-Associated Virus Serotype 9 · production yields · murine liver transduction · in vivo screening · in vitro screening · gene therapy vectors · Adeno-Associated Virus
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Virus-based gene therapy research Papers, Class of 2026. https://pri.pepkio.com/top-papers/virus-based-gene-therapy-research/2026. Accessed 2026-07-20. Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459