Circadian tumor infiltration and function of CD8+ T cells dictate immunotherapy efficacy
Most Cited Paper
in T-cell and B-cell Immunology
18 Months Post-Publication
Class of 2026
“Circadian tumor infiltration and function of CD8+ T cells dictate immunotherapy efficacy”
A research intelligence initiative by Pepkio
pri.pepkio.com/top-papers/t-cell-and-b-cell-immunology/2026/
Topics
Circadian rhythm · CD8+ T cells · tumor infiltration · immunotherapy efficacy · Circadian rhythm · leukocyte infiltration · endothelial cells · Tumor microenvironment · CAR T cell therapy · Immune checkpoint blockade · time-of-day treatment · anti-PD-1 therapy · melanoma · time-of-day-dependent T cell signatures · overall survival prediction · Circadian rhythm
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Pepkio Research Index (PRI). Topics and Trends in Most Cited T-cell and B-cell Immunology Papers, Class of 2026. https://pri.pepkio.com/top-papers/t-cell-and-b-cell-immunology/2026. Accessed 2026-07-21. Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459