GLUT1 overexpression in CAR-T cells induces metabolic reprogramming and enhances potency
Most Cited Paper
in T-cell and B-cell Immunology
18 Months Post-Publication
Class of 2026
“GLUT1 overexpression in CAR-T cells induces metabolic reprogramming and enhances potency”
A research intelligence initiative by Pepkio
pri.pepkio.com/top-papers/t-cell-and-b-cell-immunology/2026/
Topics
GLUT1 overexpression · CAR T cells · Metabolic reprogramming · glucose consumption · Glycolysis · glycolytic reserve · oxidative phosphorylation · T cell exhaustion · Th17 differentiation · glutathione-mediated ROS resistance · inosine accumulation · proinflammatory cytokines · cytotoxicity · tumor control · CAR-T cell persistence · Tumor microenvironment · glucose availability · antitumor potency
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Pepkio Research Index (PRI). Topics and Trends in Most Cited T-cell and B-cell Immunology Papers, Class of 2026. https://pri.pepkio.com/top-papers/t-cell-and-b-cell-immunology/2026. Accessed 2026-07-21. Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459