FOXO1 is a master regulator of memory programming in CAR T cells

Topics

FOXO1 · CAR T cells · Memory reprogramming · T cell exhaustion · TCF1 · TCF1 · chimeric antigen receptor · T cell persistence · memory-associated genes · FOXO1 overexpression · Chromatin accessibility · FOXO1-binding motifs · Chronic antigen stimulation · metabolic fitness · Tumor-infiltrating lymphocytes · antitumor activity · FOXO1 inhibition · gene editing · Memory reprogramming · therapeutic T cell states

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Pepkio Research Index (PRI). Topics and Trends in Most Cited T-cell and B-cell Immunology Papers, Class of 2026. https://pri.pepkio.com/top-papers/t-cell-and-b-cell-immunology/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459