Campylobacter jejuni-derived cytolethal distending toxin promotes colorectal cancer metastasis

Topics

Campylobacter jejuni · cytolethal distending toxin (CDT) · CdtB genotoxin · colorectal cancer (CRC) metastasis · JAK2-STAT3-MMP9 signaling pathway · intratumor bacteria · cdtB gene deletion (ΔcdtB) · colonic tumoroids · liver metastasis mouse model · pulmonary metastasis mouse model · bacterial translocation to extraintestinal tumors · C. jejuni-colonized mice · intracellular bacteria in solid tumors · genotoxin-driven tumor progression · MMP9 upregulation · STAT3 activation

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Pepkio Research Index (PRI). Topics and Trends in Most Cited Salmonella and Campylobacter epidemiology Papers, Class of 2026. https://pri.pepkio.com/top-papers/salmonella-and-campylobacter-epidemiology/2026. Accessed 2026-07-24.

Methodology
Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459