RNA m5C oxidation by TET2 regulates chromatin state and leukaemogenesis
Most Cited Paper
in RNA Research and Splicing
18 Months Post-Publication
Class of 2026
“RNA m5C oxidation by TET2 regulates chromatin state and leukaemogenesis”
A research intelligence initiative by Pepkio
pri.pepkio.com/top-papers/rna-research-and-splicing/2026/
Topics
TET2 · RNA m5C oxidation · chromatin state regulation · myeloid malignancy · MBD6 · H2AK119ub deubiquitination · retrotransposon RNA · DNA 5-methylcytosine oxidation · haematopoietic stem cell self-renewal · open chromatin · methyl-CpG-binding-domain protein · monoubiquitinated Lys119 of histone H2A · TET2-mutant leukaemia · TET2 deficiency · gene activation pathway · leukaemogenesis · haematopoiesis defects · therapeutic target
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Pepkio Research Index (PRI). Topics and Trends in Most Cited RNA Research and Splicing Papers, Class of 2026. https://pri.pepkio.com/top-papers/rna-research-and-splicing/2026. Accessed 2026-07-21. Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459