NSUN2 lactylation drives cancer cell resistance to ferroptosis through enhancing GCLC-dependent glutathione synthesis
Topics
NSUN2 · lactylation · ferroptosis resistance · GCLC · glutathione synthesis · m5C formation · mRNA stability · lipid peroxidation · doxorubicin · gastric cancer · NSUN2 K508R mutant · GCLC C-A mutant · NAA10 · lactytransferase · lactate treatment · tumor microenvironment · NAA10-NSUN2-GCLC axis · GSH levels
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Pepkio Research Index (PRI). Topics and Trends in Most Cited RNA modifications and cancer Papers, Class of 2026. https://pri.pepkio.com/top-papers/rna-modifications-and-cancer/2026. Accessed 2026-07-22. Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459

