Histone lactylation-regulated METTL3 promotes ferroptosis via m6A-modification on ACSL4 in sepsis-associated lung injury

Topics

histone lactylation · H3K18la · METTL3 · ferroptosis · m6A · ACSL4 · sepsis-induced acute lung injury · lactate · p300 · YTHDC1 · alveolar epithelial cells · GPR81 · mRNA stability · mitochondria-associated ferroptosis · METTL3 inhibition · septic mice model

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Pepkio Research Index (PRI). Topics and Trends in Most Cited RNA modifications and cancer Papers, Class of 2026. https://pri.pepkio.com/top-papers/rna-modifications-and-cancer/2026. Accessed 2026-07-22.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459