Peptide-Functionalized Lipid Nanoparticles for Targeted Systemic mRNA Delivery to the Brain
Most Cited Paper
in RNA Interference and Gene Delivery
18 Months Post-Publication
Class of 2026
“Peptide-Functionalized Lipid Nanoparticles for Targeted Systemic mRNA Delivery to the Brain”
A research intelligence initiative by Pepkio
pri.pepkio.com/top-papers/rna-interference-and-gene-delivery/2026/
Topics
Peptide-functionalized nanoparticles · Systemic administration · Blood-brain barrier · RVG29 peptide · T7 peptide · AP2 peptide · mApoE peptide · click chemistry · brain endothelial cells · neuronal transfection · serum protein adsorption · intracellular trafficking · endothelial transcytosis · Extracellular vesicles (EVs) · hepatic accumulation · receptor targeting · Non-viral gene delivery vectors
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Pepkio Research Index (PRI). Topics and Trends in Most Cited RNA Interference and Gene Delivery Papers, Class of 2026. https://pri.pepkio.com/top-papers/rna-interference-and-gene-delivery/2026. Accessed 2026-07-21. Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459