Accelerating ionizable lipid discovery for mRNA delivery using machine learning and combinatorial chemistry

Topics

Ionizable lipids · mRNA delivery · machine learning · High-throughput screening · Lipid nanoparticles · structure-activity relationship · High-throughput screening · Lipid design · Transfection · predictive modeling · Lipid design · nucleic acid therapeutics · Formulation · In silico screening · chemical space exploration

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Pepkio Research Index (PRI). Topics and Trends in Most Cited RNA Interference and Gene Delivery Papers, Class of 2026. https://pri.pepkio.com/top-papers/rna-interference-and-gene-delivery/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459