Targeting the transferrin receptor to transport antisense oligonucleotides across the mammalian blood-brain barrier
Most Cited Paper
in RNA Interference and Gene Delivery
18 Months Post-Publication
Class of 2026
“Targeting the transferrin receptor to transport antisense oligonucleotides across the mammalian blood-brain barrier”
A research intelligence initiative by Pepkio
pri.pepkio.com/top-papers/rna-interference-and-gene-delivery/2026/
Topics
antisense oligonucleotides · Blood-brain barrier · Transferrin receptor 1 · oligonucleotide transport vehicle · Human TFRC knockin mice · Malat1 · Systemic administration · intrathecal delivery · CNS biodistribution · endothelial cells · neurons · astrocytes · microglia · oligodendrocytes · cynomolgus macaques · bivalent TfR antibody · RNA-targeted therapies · intravenous administration · quadriceps muscle · cardiac muscle
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Pepkio Research Index (PRI). Topics and Trends in Most Cited RNA Interference and Gene Delivery Papers, Class of 2026. https://pri.pepkio.com/top-papers/rna-interference-and-gene-delivery/2026. Accessed 2026-07-21. Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459