An AAV capsid reprogrammed to bind human transferrin receptor mediates brain-wide gene delivery
Most Cited Paper
in RNA Interference and Gene Delivery
18 Months Post-Publication
Class of 2026
“An AAV capsid reprogrammed to bind human transferrin receptor mediates brain-wide gene delivery”
A research intelligence initiative by Pepkio
pri.pepkio.com/top-papers/rna-interference-and-gene-delivery/2026/
Topics
Adeno-associated virus (AAV) · BI-hTFR1 · Transferrin receptor 1 · Transferrin receptor 1 · Blood-brain barrier · CNS drug delivery · transcytosis · human brain endothelial cells · Adeno-associated virus (AAV) · Human TFRC knockin mice · CNS drug delivery · GBA1 gene · Gaucher disease · Parkinson's disease · glucocerebrosidase activity · cerebrospinal fluid · CNS drug delivery · receptor-mediated transport
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Pepkio Research Index (PRI). Topics and Trends in Most Cited RNA Interference and Gene Delivery Papers, Class of 2026. https://pri.pepkio.com/top-papers/rna-interference-and-gene-delivery/2026. Accessed 2026-07-21. Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459