Metabolic Recoding of NSUN2‐Mediated m<sup>5</sup>C Modification Promotes the Progression of Colorectal Cancer via the NSUN2/YBX1/m<sup>5</sup>C‐ENO1 Positive Feedback Loop
Most Cited Paper
in RNA and protein synthesis mechanisms
18 Months Post-Publication
Class of 2026
“Metabolic Recoding of NSUN2‐Mediated m<sup>5</sup>C Modification Promotes the Progression of Colorectal Cancer via the NSUN2/YBX1/m<sup>5</sup>C‐ENO1 Positive Feedback Loop”
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pri.pepkio.com/top-papers/rna-and-protein-synthesis-mechanisms/2026/
Topics
5-methylcytosine (m5C) · NSUN2 · YBX1 · ENO1 · colorectal cancer (CRC) · m5C methyltransferase · m5C reader protein · glucose metabolism reprogramming · lactic acid production · histone H3K18 lactylation (H3K18la) · NSUN2 K356 lactylation · NSUN2/YBX1/m5C-ENO1 positive feedback loop · post-transcriptional regulation · metabolic reprogramming · epigenetic remodeling · RNA modifications · NSUN2 inhibitor · immunotherapy combination · oncogenic function · lactylation-mediated transcriptional activation
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Pepkio Research Index (PRI). Topics and Trends in Most Cited RNA and protein synthesis mechanisms Papers, Class of 2026. https://pri.pepkio.com/top-papers/rna-and-protein-synthesis-mechanisms/2026. Accessed 2026-07-15. Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459