Adding α,α-disubstituted and β-linked monomers to the genetic code of an organism

Topics

tRNA display · orthogonal aminoacyl-tRNA synthetases · non-canonical monomers · β-amino acids · α,α-disubstituted amino acids · β-hydroxy acids · orthogonal tRNAs · genetic code engineering · ribosomal substrates · evolutionary deadlock · site-specific incorporation · Escherichia coli · non-canonical amino acids · synthetase selection · tRNA acylation · macrocyclic peptides · depsipeptides · encoded polymer synthesis

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Pepkio Research Index (PRI). Topics and Trends in Most Cited RNA and protein synthesis mechanisms Papers, Class of 2026. https://pri.pepkio.com/top-papers/rna-and-protein-synthesis-mechanisms/2026. Accessed 2026-07-15.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459