The microbial metabolite agmatine acts as an FXR agonist to promote polycystic ovary syndrome in female mice

Topics

agmatine · FXR agonist · Polycystic ovary syndrome · microbial metabolite · gut microbiota · farnesoid X receptor · PCOS mouse model · microbiome-host interaction · metabolite signaling · nuclear receptor activation · ovarian dysfunction · gut-ovary axis · bacterial metabolism · Endocrine disruption

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Pepkio Research Index (PRI). Topics and Trends in Most Cited Reproductive Biology and Fertility Papers, Class of 2026. https://pri.pepkio.com/top-papers/reproductive-biology-and-fertility/2026. Accessed 2026-07-17.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459