Homodimerization of CB2 cannabinoid receptor triggered by a bivalent ligand enhances cellular signaling
#4PRI RANKED
Most Cited Paper
in Receptor Mechanisms and Signaling
18 Months Post-Publication
Class of 2026
“Homodimerization of CB2 cannabinoid receptor triggered by a bivalent ligand enhances cellular signaling”
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Topics
CB2 cannabinoid receptor · homobivalent ligand · chromenopyrazole · GPCR homodimerization · orthosteric site · membrane-oriented pocket · TM1/7 interface · Gi signaling · β-arrestin recruitment · Conformational change · receptor oligomerization · bivalent ligand pharmacology · protomer binding · TM1/7 interface · dimerization dynamics modulation · enhanced signaling potency · Allosteric site
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Receptor Mechanisms and Signaling Papers, Class of 2026. https://pri.pepkio.com/top-papers/receptor-mechanisms-and-signaling/2026. Accessed 2026-07-29. Methodology Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459