Ligand efficacy modulates conformational dynamics of the µ-opioid receptor
Most Cited Paper
in Receptor Mechanisms and Signaling
18 Months Post-Publication
Class of 2026
“Ligand efficacy modulates conformational dynamics of the µ-opioid receptor”
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Topics
μ-opioid receptor · Ligand efficacy · Conformational change · double electron–electron resonance · single-molecule fluorescence resonance energy transfer · Ligand efficacy · cytoplasmic face conformations · pre-activated conformation · fully activated conformation · G-protein binding · GDP affinity · ternary complex · β-arrestin-1 · Gi protein
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Receptor Mechanisms and Signaling Papers, Class of 2026. https://pri.pepkio.com/top-papers/receptor-mechanisms-and-signaling/2026. Accessed 2026-07-29. Methodology Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459