Two-stage evolution of mammalian adipose tissue thermogenesis
Topics
brown adipose tissue · BAT thermogenesis · Uncoupling protein 1 · Uncoupling protein 1 · marsupials · eutherian mammals · nonthermogenic UCP1 variant · beige adipose tissue · transcriptomic BAT signature · ancestral sequence reconstruction · therian ancestor · common eutherian ancestor · BAT thermogenesis · two-stage evolution · prethermogenic stage · Cold stress · Heat stress · mammalian body temperature regulation
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Physiological and biochemical adaptations Papers, Class of 2026. https://pri.pepkio.com/top-papers/physiological-and-biochemical-adaptations/2026. Accessed 2026-10-24. Methodology Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459

