Lactate dehydrogenase A (LDHA)-mediated lactate generation promotes pulmonary vascular remodeling in pulmonary hypertension
Most Cited Paper
in Physiological and biochemical adaptations
18 Months Post-Publication
Class of 2026
“Lactate dehydrogenase A (LDHA)-mediated lactate generation promotes pulmonary vascular remodeling in pulmonary hypertension”
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Topics
lactate dehydrogenase A (LDHA) · Lactate accumulation · pulmonary vascular remodeling · pulmonary hypertension · pulmonary artery smooth muscle cells (PASMCs) · Akt signaling pathway · Hypoxia · right ventricular dysfunction · LDHA knockdown · Sugen/hypoxia mouse model · monocrotaline (MCT)-induced rat model · chronic hypoxia-induced mouse model · LDHA inhibitor · Metabolic adaptation · cell proliferation · cell migration · right heart catheterization · Lactate accumulation
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Physiological and biochemical adaptations Papers, Class of 2026. https://pri.pepkio.com/top-papers/physiological-and-biochemical-adaptations/2026. Accessed 2026-10-24. Methodology Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459