Gene expression responses of CF airway epithelial cells exposed to elexacaftor/tezacaftor/ivacaftor suggest benefits beyond improved CFTR channel function
Most Cited Paper
in Pediatric health and respiratory diseases
18 Months Post-Publication
Class of 2026
“Gene expression responses of CF airway epithelial cells exposed to elexacaftor/tezacaftor/ivacaftor suggest benefits beyond improved CFTR channel function”
A research intelligence initiative by Pepkio
pri.pepkio.com/top-papers/pediatric-health-and-respiratory-diseases/2026/
Topics
Elexacaftor/tezacaftor/ivacaftor · CFTR channel function · CF airway epithelial cells (AECs) · gene expression profiling · beta-defensin 1 (hBD-1) · bacterial infection resistance · MMP10 · MMP12 · lung tissue damage · airway inflammation · proinflammatory cytokine secretion · CFTR modulator therapy · Cystic fibrosis
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Pediatric health and respiratory diseases Papers, Class of 2026. https://pri.pepkio.com/top-papers/pediatric-health-and-respiratory-diseases/2026. Accessed 2026-07-13. Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459