Antibiotic-driven dysbiosis in early life disrupts indole-3-propionic acid production and exacerbates allergic airway inflammation in adulthood
#2PRI RANKED
Most Cited Paper
in Pediatric health and respiratory diseases
18 Months Post-Publication
Class of 2026
“Antibiotic-driven dysbiosis in early life disrupts indole-3-propionic acid production and exacerbates allergic airway inflammation in adulthood”
A research intelligence initiative by Pepkio
pri.pepkio.com/top-papers/pediatric-health-and-respiratory-diseases/2026/
Topics
antibiotic-driven dysbiosis · Microbiome disruption · indole-3-propionic acid · allergic airway inflammation · gut-lung axis · tryptophan metabolism · Gut microbiome · microbial metabolite deficiency · Germ-free mice · asthma pathogenesis · aryl hydrocarbon receptor signaling · Th2 immune response · Airway hyperresponsiveness · fecal metabolomics · Antibiotic use · microbiota-derived indole metabolites · Immune system development · Short-chain fatty acid-producing bacteria · bacterial tryptophan catabolism · mucosal immunity
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Pediatric health and respiratory diseases Papers, Class of 2026. https://pri.pepkio.com/top-papers/pediatric-health-and-respiratory-diseases/2026. Accessed 2026-07-13. Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459