Ligand efficacy modulates conformational dynamics of the µ-opioid receptor

Topics

μ-opioid receptor · ligand efficacy · Conformational changes · double electron–electron resonance · single-molecule fluorescence resonance energy transfer · intrinsic efficacy · cytoplasmic face conformations · pre-activated conformation · fully activated conformation · G protein coupling · GDP affinity · ternary complex · β-arrestin · G protein coupling

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Pepkio Research Index (PRI). Topics and Trends in Most Cited Neuropeptides and Animal Physiology Papers, Class of 2026. https://pri.pepkio.com/top-papers/neuropeptides-and-animal-physiology/2026. Accessed 2026-07-31.

Methodology
Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459