Inputs to the locus coeruleus from the periaqueductal gray and rostroventral medulla shape opioid-mediated descending pain modulation
Most Cited Paper
in Neuropeptides and Animal Physiology
18 Months Post-Publication
Class of 2026
“Inputs to the locus coeruleus from the periaqueductal gray and rostroventral medulla shape opioid-mediated descending pain modulation”
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Topics
locus coeruleus · periaqueductal gray · rostroventral medulla · Pain modulation · noradrenergic neurons · Antinociception · Ventrolateral periaqueductal gray (vlPAG) · Antinociception · opioid-sensitive inhibitory input · disinhibition · bifurcating outputs · descending serotonergic pathways · monoaminergic modulation · Antinociception · pain-related activity · excitatory output from vlPAG to LC · RVM inhibitory input · Pain modulation
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Neuropeptides and Animal Physiology Papers, Class of 2026. https://pri.pepkio.com/top-papers/neuropeptides-and-animal-physiology/2026. Accessed 2026-07-31. Methodology Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459