The pharmacological basis for nonpeptide agonism of the GLP-1 receptor by orforglipron
Most Cited Paper
in Neuropeptides and Animal Physiology
18 Months Post-Publication
Class of 2026
“The pharmacological basis for nonpeptide agonism of the GLP-1 receptor by orforglipron”
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Topics
Orforglipron · GLP-1 receptor · nonpeptide agonists · GLP-1 receptor · Type 2 diabetes mellitus · obesity · competition binding experiments · intrinsic efficacy · β-arrestin · receptor occupancy · CRISPR-Cas9 gene editing · Glp1r S33W · semaglutide · Diet-induced obesity · oral bioavailability · target engagement · Signal transduction · Glucose tolerance · peptide receptors
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Neuropeptides and Animal Physiology Papers, Class of 2026. https://pri.pepkio.com/top-papers/neuropeptides-and-animal-physiology/2026. Accessed 2026-07-31. Methodology Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459