Neuronal substance P drives metastasis through an extracellular RNA–TLR7 axis

🏆 Top 10📊 OpenAlex

#1PRI RANKED

Most Cited Paper

in Neuropeptides and Animal Physiology

18 Months Post-Publication

Class of 2026

“Neuronal substance P drives metastasis through an extracellular RNA–TLR7 axis”

AuthorsVeena Padmanaban et al.

Sohail F. Tavazoie

JournalNature

The Rockefeller University

Citations127

DOI10.1038/s41586-024-07767-5

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Topics

Substance P · metastasis · extracellular RNA · Toll-like receptor 7 · Neuronal modulation · Tumor innervation · neuropeptide · Toll-like receptor 7 · cancer progression · Neuroimmune interaction · RNA-mediated signaling · Sensory neurons · tumor microenvironment · Neurokinin 1 receptor (NK1R) · extracellular RNA · innate immunity

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Pepkio Research Index (PRI). Topics and Trends in Most Cited Neuropeptides and Animal Physiology Papers, Class of 2026. https://pri.pepkio.com/top-papers/neuropeptides-and-animal-physiology/2026. Accessed 2026-07-31.

Methodology
Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459