A humanized mouse that mounts mature class-switched, hypermutated and neutralizing antibody responses
Most Cited Paper
in Monoclonal and Polyclonal Antibodies Research
18 Months Post-Publication
Class of 2026
“A humanized mouse that mounts mature class-switched, hypermutated and neutralizing antibody responses”
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pri.pepkio.com/top-papers/monoclonal-and-polyclonal-antibodies-research/2026/
Topics
Humanized mouse model · Kit W-41J mutant immunodeficient mice · human cord blood CD34+ cell engraftment · 17β-estradiol conditioning · genetic myeloablation · non-γ-irradiation conditioning · marginal zone B cells · germinal center B cells · T follicular helper cells · Peyer's patches reconstitution · human thymic epithelial cells · immune repertoire · somatic hypermutation · class switch recombination · memory B cells · flagellin immunization · Pfizer-BioNTech vaccine · SARS-CoV-2 Spike S1 receptor-binding domain neutralizing antibodies · pristane-induced lupus autoimmunity · APRIL BAFF TGF-β IL-4 IFN-γ cytokine profile
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Monoclonal and Polyclonal Antibodies Research Papers, Class of 2026. https://pri.pepkio.com/top-papers/monoclonal-and-polyclonal-antibodies-research/2026. Accessed 2026-07-15. Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459