A unique serum IgG glycosylation signature predicts development of Crohn’s disease and is associated with pathogenic antibodies to mannose glycan
Most Cited Paper
in Monoclonal and Polyclonal Antibodies Research
18 Months Post-Publication
Class of 2026
“A unique serum IgG glycosylation signature predicts development of Crohn’s disease and is associated with pathogenic antibodies to mannose glycan”
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pri.pepkio.com/top-papers/monoclonal-and-polyclonal-antibodies-research/2026/
Topics
Fc glycosylation · agalactosylation · anti-Saccharomyces cerevisiae antibodies (ASCA) · PREDICTS cohort · preclinical Crohn's disease phase · IgG2 Fc glycan trait · mannose glycan recognition · FcγR-dependent signaling · NF-κB signaling · CARD9 signaling · inflammasome activation · dendritic cell reprogramming · natural killer cell activation · adoptive antibody transfer mouse model · FcγR-deficient mice · anti-mannan antibodies · glycome-ASCA hub · serum biomarker for disease prediction · intestinal inflammation susceptibility · proinflammatory antibody glycoform
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Monoclonal and Polyclonal Antibodies Research Papers, Class of 2026. https://pri.pepkio.com/top-papers/monoclonal-and-polyclonal-antibodies-research/2026. Accessed 2026-07-15. Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459