De novo generation of SARS-CoV-2 antibody CDRH3 with a pre-trained generative large language model
Most Cited Paper
in Monoclonal and Polyclonal Antibodies Research
18 Months Post-Publication
Class of 2026
“De novo generation of SARS-CoV-2 antibody CDRH3 with a pre-trained generative large language model”
A research intelligence initiative by Pepkio
pri.pepkio.com/top-papers/monoclonal-and-polyclonal-antibodies-research/2026/
Topics
PALM-H3 · CDR3 · generative large language model · A2binder · antibody-antigen binding prediction · SARS-CoV-2 spike protein · XBB · antibody-antigen binding prediction · antibody-antigen binding prediction · neutralization capability · Roformer architecture · attention mechanism interpretability · in-silico antibody design · artificial antibody generation · antigen specificity · Alpha variant · Delta variant · wild-type SARS-CoV-2 · antibody language model · CDR3
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Monoclonal and Polyclonal Antibodies Research Papers, Class of 2026. https://pri.pepkio.com/top-papers/monoclonal-and-polyclonal-antibodies-research/2026. Accessed 2026-07-15. Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459