Whole-brain spatial transcriptional analysis at cellular resolution

Topics

TRISCO · tissue-clearing method · whole-brain 3D RNA imaging · in situ hybridization chain reaction · Spatial transcriptomics · RNA integrity preservation · uniform RNA labeling · tissue transparency enhancement · cell-identity markers · Non-coding RNAs · activity-dependent RNAs · single-cell resolution · intact tissue volumes · Tris buffer-mediated retention · cleared organs

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Pepkio Research Index (PRI). Topics and Trends in Most Cited Molecular Biology Techniques and Applications Papers, Class of 2026. https://pri.pepkio.com/top-papers/molecular-biology-techniques-and-applications/2026. Accessed 2026-07-24.

Methodology
Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459