Engineered extracellular vesicles for targeted reprogramming of cancer-associated fibroblasts to potentiate therapy of pancreatic cancer
Topics
Engineered extracellular vesicles · cancer-associated fibroblasts · CAF reprogramming · tumor microenvironment · pancreatic cancer · bone marrow mesenchymal stem cells · miR-138-5p · pirfenidone · integrin α5-targeting peptides · FERMT2-TGFBR1 complex · TGF-β signaling pathway · FERMT2-PYCR1 complex · proline-mediated collagen synthesis · orthotopic stroma-rich mouse model · patient-derived xenograft · gemcitabine perfusion · tumor hypoxia · chemotherapy sensitization · IEVs-PFD/138
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Pepkio Research Index (PRI). Topics and Trends in Most Cited MicroRNA in disease regulation Papers, Class of 2026. https://pri.pepkio.com/top-papers/microrna-in-disease-regulation/2026. Accessed 2026-07-20. Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459

