Natural Products Have Increased Rates of Clinical Trial Success throughout the Drug Development Process
Most Cited Paper
in Microbial Natural Products and Biosynthesis
18 Months Post-Publication
Class of 2026
“Natural Products Have Increased Rates of Clinical Trial Success throughout the Drug Development Process”
A research intelligence initiative by Pepkio
pri.pepkio.com
Topics
natural products · clinical trial success rate · drug development process · NP-derived compounds · synthetic compounds · patent applications · clinical trial phases I to III · in vitro toxicity studies · in silico toxicity studies · drug approval · early-stage drug discovery · late-stage drug discovery · compound toxicity comparison · NP-based drug development
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Microbial Natural Products and Biosynthesis Papers, Class of 2026. https://pri.pepkio.com/top-papers/microbial-natural-products-and-biosynthesis/2026. Accessed 2026-10-24. Methodology Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459