Complete biosynthesis of QS-21 in engineered yeast
Most Cited Paper
in Microbial Natural Products and Biosynthesis
18 Months Post-Publication
Class of 2026
“Complete biosynthesis of QS-21 in engineered yeast”
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Topics
QS-21 · vaccine adjuvant · saponin · Chilean soapbark tree · yeast biosynthesis · pathway engineering · heterologous expression · terpene synthase · cytochrome P450 · nucleotide sugar synthases · glycosyltransferases · coenzyme A ligase · acyltransferases · polyketide synthase · subcellular compartmentalization · endoplasmic reticulum · substrate promiscuity · structural analogues · structure-activity relationships · metabolic flux tuning
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Microbial Natural Products and Biosynthesis Papers, Class of 2026. https://pri.pepkio.com/top-papers/microbial-natural-products-and-biosynthesis/2026. Accessed 2026-10-24. Methodology Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459