Complete biosynthesis of QS-21 in engineered yeast

Topics

QS-21 · vaccine adjuvant · saponin biosynthesis · Engineered yeast · Heterologous expression · Terpene synthase · P450s · nucleotide sugar synthases · glycosyltransferases · coenzyme A ligase · acyl transferases · polyketide synthases · Compartmentalization · endoplasmic reticulum · pathway flux tuning · structural analogues · enzyme promiscuity · Chilean soapbark tree · Bioprocessing · structure-activity relationship

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Pepkio Research Index (PRI). Topics and Trends in Most Cited Microbial Metabolic Engineering and Bioproduction Papers, Class of 2026. https://pri.pepkio.com/top-papers/microbial-metabolic-engineering-and-bioproduction/2026. Accessed 2026-07-29.

Methodology
Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459