Pyrimidines maintain mitochondrial pyruvate oxidation to support de novo lipogenesis
Most Cited Paper
in Metabolism and Genetic Disorders
18 Months Post-Publication
Class of 2026
“Pyrimidines maintain mitochondrial pyruvate oxidation to support de novo lipogenesis”
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pri.pepkio.com
Topics
pyrimidines · mitochondrial pyruvate oxidation · de novo lipogenesis · Pyruvate dehydrogenase · PDH activity · thiamine pyrophosphate · TPP synthesis · TPK1 · TPK1 · Uridine triphosphate (UTP) · Uridine triphosphate (UTP) · Tricarboxylic acid cycle · Tricarboxylic acid cycle · Thiamine · Thiamine · adipocyte differentiation · purine-pyrimidine metabolism · metabolic cofactor regulation
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Metabolism and Genetic Disorders Papers, Class of 2026. https://pri.pepkio.com/top-papers/metabolism-and-genetic-disorders/2026. Accessed 2026-07-24. Methodology Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459