Engineering exosomes derived from TNF-α preconditioned IPFP-MSCs enhance both yield and therapeutic efficacy for osteoarthritis

🏆 Top 20📊 OpenAlex

Most Cited Paper

in Mesenchymal stem cell research

18 Months Post-Publication

Class of 2026

“Engineering exosomes derived from TNF-α preconditioned IPFP-MSCs enhance both yield and therapeutic efficacy for osteoarthritis”

AuthorsJiangyi Wu, Jinhui Wu, Wei Xiang et al.

Yongqian Wang, Siru Zhou, Zhenhong Ni

JournalJournal of Nanobiotechnology

Chinese Academy of Medical Sciences and Peking Union Medical College

Citations48

DOI10.1186/s12951-024-02795-9

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Topics

TNF-α preconditioning · IPFP-MSCs · MSC-derived exosomes · Osteoarthritis · exosome yield optimization · PI3K/AKT signaling pathway · ATG16L1 · ATG16L1 · exosome secretion · Intra-articular injection · Cartilage degradation · LRP1 · LRP1 · chondroprotective effects · RNA sequencing · Proteomics · pro-inflammatory preconditioning · cartilage homeostasis · OA mouse model

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Pepkio Research Index (PRI). Topics and Trends in Most Cited Mesenchymal stem cell research Papers, Class of 2026. https://pri.pepkio.com/top-papers/mesenchymal-stem-cell-research/2026. Accessed 2026-07-31.

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Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459