Feasibility, safety, and impact of the RTS,S/AS01E malaria vaccine when implemented through national immunisation programmes: evaluation of cluster-randomised introduction of the vaccine in Ghana, Kenya, and Malawi

Topics

RTS,S/AS01E vaccine · cluster-randomised introduction · national immunisation programmes · pilot implementation schemes · vaccine safety signals · meningitis · cerebral malaria · sex-differential mortality · four-dose vaccination schedule · hospital admission with severe malaria · all-cause mortality · vaccination coverage · sentinel hospital surveillance · Incidence rate ratio · age-eligible cohorts · vaccine impact evaluation · moderate-to-high malaria transmission areas · WHO recommendation · implementation feasibility · Cluster-randomized trial