Decreased lipidated ApoE-receptor interactions confer protection against pathogenicity of ApoE and its lipid cargoes in lysosomes
Most Cited Paper
in Lipid Membrane Structure and Behavior
18 Months Post-Publication
Class of 2026
“Decreased lipidated ApoE-receptor interactions confer protection against pathogenicity of ApoE and its lipid cargoes in lysosomes”
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Topics
apolipoprotein E (APOE) · late-onset Alzheimer's disease (LOAD) · ApoE isoforms · low-density lipoprotein receptor (LDLR) · lipidated ApoE2 (lipApoE2) · LDLR recycling defects · cholesteryl esters (CEs) · polyunsaturated fatty acids (PUFAs) · lipofuscinosis · lipid peroxidation · lysosomal pathology · tau fibrils · APOE4 mouse model · intrahippocampal injection · Christchurch mutation · endolysosomal targeting · ApoE-receptor interactions · neurodegeneration · human neurons · allelic series
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Lipid Membrane Structure and Behavior Papers, Class of 2026. https://pri.pepkio.com/top-papers/lipid-membrane-structure-and-behavior/2026. Accessed 2026-10-24. Methodology Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459