A Foundation Model Identifies Broad-Spectrum Antimicrobial Peptides against Drug-Resistant Bacterial Infection

🏆 Top 10📊 OpenAlex

#5PRI RANKED

Most Cited Paper

in Lipid Membrane Structure and Behavior

18 Months Post-Publication

Class of 2026

“A Foundation Model Identifies Broad-Spectrum Antimicrobial Peptides against Drug-Resistant Bacterial Infection”

AuthorsTingting Li, Xuanbai Ren et al.

Xiangxiang Zeng, Junfeng Shi, Feixiong Cheng

JournalNature Communications

Affiliated Hospital of Hunan University

Citations76

DOI10.1038/s41467-024-51933-2

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Topics

deepAMP · antimicrobial peptides · peptide language model · deep generative framework · antimicrobial resistance · membrane-disrupting ability · T1-AMP · T2-AMP · cross-optimization-validation · penetratin · S. aureus · K. pneumoniae · P. aeruginosa · Gram-positive bacteria · Gram-negative bacteria · ciprofloxacin · skin wound infection · wound mouse model · broad-spectrum activity · drug-resistant bacteria

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Pepkio Research Index (PRI). Topics and Trends in Most Cited Lipid Membrane Structure and Behavior Papers, Class of 2026. https://pri.pepkio.com/top-papers/lipid-membrane-structure-and-behavior/2026. Accessed 2026-10-24.

Methodology
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