Breaking the final barrier: Evolution of cationic and ionizable lipid structure in lipid nanoparticles to escape the endosome
#4PRI RANKED
Most Cited Paper
in Lipid Membrane Structure and Behavior
18 Months Post-Publication
Class of 2026
“Breaking the final barrier: Evolution of cationic and ionizable lipid structure in lipid nanoparticles to escape the endosome”
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Topics
cationic lipids · Ionizable lipids · Lipid nanoparticles · Endosomal release · lipid structure evolution · LNP design · intracellular delivery · pKa optimization · lipid chemistry · nucleic acid delivery · Membrane fusion · pH-responsive lipids · Transfection efficiency · lipid-mediated delivery · endosome membrane disruption
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Lipid Membrane Structure and Behavior Papers, Class of 2026. https://pri.pepkio.com/top-papers/lipid-membrane-structure-and-behavior/2026. Accessed 2026-10-24. Methodology Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459