Lysosomal damage sensing and lysophagy initiation by SPG20-ITCH
Topics
SPG20 · ITCH · lysophagy · Lysosomal rupture · lipid-packing defects · Amphipathic helices · IST1 · lysine-63-linked ubiquitin chains · lipid bilayer perturbations · lysosomal damage sensing · membrane repair · lipid peroxidation · ubiquitin-triggered lysophagy · lysosomal damage response · neurodegeneration
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Lipid Membrane Structure and Behavior Papers, Class of 2026. https://pri.pepkio.com/top-papers/lipid-membrane-structure-and-behavior/2026. Accessed 2026-10-24. Methodology Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459

