Glutamate acts on acid-sensing ion channels to worsen ischaemic brain injury
Topics
glutamate · Acid-sensing ion channels · Acid-sensing ion channels · ASIC1a · NMDA receptor · NMDA receptor · l-AP5 · Ischemic stroke · acidosis-induced neurotoxicity · Positive allosteric modulators · glutamate-binding cavity · site-directed mutagenesis · Structure-based drug design · computational drug screening · LK-2 · ASIC1a knockout · Infarct volume · Behavioral recovery · proton affinity · open probability
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Ion channel regulation and function Papers, Class of 2026. https://pri.pepkio.com/top-papers/ion-channel-regulation-and-function/2026. Accessed 2026-07-22. Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459

