Interplay of Nav1.8 and Nav1.7 channels drives neuronal hyperexcitability in neuropathic pain
Most Cited Paper
in Ion channel regulation and function
18 Months Post-Publication
Class of 2026
“Interplay of Nav1.8 and Nav1.7 channels drives neuronal hyperexcitability in neuropathic pain”
A research intelligence initiative by Pepkio
pri.pepkio.com/top-papers/ion-channel-regulation-and-function/2026/
Topics
Nav1.8 · Nav1.7 · dorsal root ganglion neurons · neuronal hyperexcitability · neuropathic pain · dynamic clamp · Nav1.7L848H · Gain-of-function mutation · inherited erythromelalgia · action potential threshold · channel open-probability · rheobase · subthreshold membrane potential oscillations · firing probability · kinetic model · Nav1.8 conductance reduction · small DRG neurons · electrogenesis · Voltage-gated sodium channels
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Ion channel regulation and function Papers, Class of 2026. https://pri.pepkio.com/top-papers/ion-channel-regulation-and-function/2026. Accessed 2026-07-22. Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459