Blockade of LAG-3 and PD-1 leads to co-expression of cytotoxic and exhaustion gene modules in CD8+ T cells to promote antitumor immunity
Most Cited Paper
in Immune Cell Function and Interaction
18 Months Post-Publication
Class of 2026
“Blockade of LAG-3 and PD-1 leads to co-expression of cytotoxic and exhaustion gene modules in CD8+ T cells to promote antitumor immunity”
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pri.pepkio.com/top-papers/immune-cell-function-and-interaction/2026/
Topics
LAG-3 blockade · PD-1/PD-L1 blockade · dual checkpoint inhibition · CD8+ T cell exhaustion · cytotoxic gene module · exhaustion gene module · Antitumor immunity · Immune checkpoint blockade
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Immune Cell Function and Interaction Papers, Class of 2026. https://pri.pepkio.com/top-papers/immune-cell-function-and-interaction/2026. Accessed 2026-07-15. Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459