mRNA-LNP HIV-1 trimer boosters elicit precursors to broad neutralizing antibodies

🏆 Top 10📊 OpenAlex

Most Cited Paper

in HIV Research and Treatment

18 Months Post-Publication

Class of 2026

“mRNA-LNP HIV-1 trimer boosters elicit precursors to broad neutralizing antibodies”

AuthorsZhenfei Xie, Ying-Cing Lin, Jon M Steichen, Gabriel Ozorowski et al.

Zhenfei Xie, Ying‐Cing Lin, Jon M. Steichen, Gabriel Ozorowski, Andrew B. Ward, William R. Schief, Facundo D. Batista

JournalScience

Ragon Institute

Citations50

DOI10.1126/science.adk0582

A research intelligence initiative by Pepkio

pri.pepkio.com/top-papers/hiv-research-and-treatment/2026/

Topics

mRNA-LNP delivery · Germline-targeting immunogens · N332-GT5 trimer · Broadly neutralizing antibodies (bNAbs) · V3-glycan epitope · Humanized mouse models · B cell lineage · Germinal center reactions · epitope masking · B cell receptor modification · somatic hypermutation · affinity maturation · prime-boost immunization strategy · off-target V1-binding responses · B cell lineage · HIV vaccine · lipid nanoparticle formulation · cross-reactivity minimization · HIV vaccine · Broadly neutralizing antibodies (bNAbs)

Share on X

Cite this ranking

Pepkio Research Index (PRI). Topics and Trends in Most Cited HIV Research and Treatment Papers, Class of 2026. https://pri.pepkio.com/top-papers/hiv-research-and-treatment/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459