Cancer-associated fibroblasts promote the progression and chemoresistance of HCC by inducing IGF-1
Most Cited Paper
in Growth Hormone and Insulin-like Growth Factors
18 Months Post-Publication
Class of 2026
“Cancer-associated fibroblasts promote the progression and chemoresistance of HCC by inducing IGF-1”
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Topics
cancer-associated fibroblasts · Hepatocellular carcinoma · Interleukin-6 · Insulin-like growth factor 1 · Insulin-like growth factor 1 receptor · NT157 · STAT3 phosphorylation · IRS-1 degradation · AKT signalling · ERK-dependent manner · sorafenib · chemoresistance · IL-6-IGF-1 axis · CAF-tumor cell crosstalk · autocrine signaling · IGF-1R inhibitors · ERK MAPK pathway · sorafenib resistance
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Growth Hormone and Insulin-like Growth Factors Papers, Class of 2026. https://pri.pepkio.com/top-papers/growth-hormone-and-insulin-like-growth-factors/2026. Accessed 2026-10-24. Methodology Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459