HBO1 catalyzes lysine lactylation and mediates histone H3K9la to regulate gene transcription
#5PRI RANKED
Most Cited Paper
in Genomics and Chromatin Dynamics
18 Months Post-Publication
Class of 2026
“HBO1 catalyzes lysine lactylation and mediates histone H3K9la to regulate gene transcription”
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Topics
lysine lactylation · HBO1 · lysine lactyltransferase · histone H3K9la · E508 catalytic site · Quantitative proteomics · JADE1 · BRPF2 · scaffold proteins · CUT&Tag · transcription start sites · Transcriptional regulation · tumorigenesis · HBO1 knockout · Histone modifications · metabolic regulation of gene expression
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Genomics and Chromatin Dynamics Papers, Class of 2026. https://pri.pepkio.com/top-papers/genomics-and-chromatin-dynamics/2026. Accessed 2026-10-24. Methodology Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459