A secondary mechanism of action for triazole antifungals in Aspergillus fumigatus mediated by hmg1
Topics
Azole antifungals · Aspergillus fumigatus · Ergosterol biosynthesis · CYP51 · Sterol 14-demethylase · HMG-CoA reductase · sterol sensing domain · sterol intermediate perturbations · Insulin-Induced Gene orthologs · negative feedback regulation · invasive aspergillosis · antifungal resistance · HMG-CoA reductase mutations · sterol sensing domain mutations · secondary mechanism of action · Pathway downregulation
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Fungal Biology and Applications Papers, Class of 2026. https://pri.pepkio.com/top-papers/fungal-biology-and-applications/2026. Accessed 2026-07-22. Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459

