Inhibition of GPX4 enhances CDK4/6 inhibitor and endocrine therapy activity in breast cancer

Topics

GPX4 · CDK4/6 inhibitor · endocrine therapy · estrogen receptor positive breast cancer · palbociclib · giredestrant · Ferroptosis · genome-wide CRISPR screens · oxidative stress · lipid peroxidation · AGPAT3 · ACSL4 · triple negative breast cancer · CDK4/6 inhibitor resistance · lipid metabolism · peroxisome · Cytostasis · GPX4 inhibition

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Pepkio Research Index (PRI). Topics and Trends in Most Cited Estrogen and related hormone effects Papers, Class of 2026. https://pri.pepkio.com/top-papers/estrogen-and-related-hormone-effects/2026. Accessed 2026-07-31.

Methodology
Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459