PARP1-DNA co-condensation drives DNA repair site assembly to prevent disjunction of broken DNA ends
#3PRI RANKED
Most Cited Paper
in DNA Repair Mechanisms
18 Months Post-Publication
Class of 2026
“PARP1-DNA co-condensation drives DNA repair site assembly to prevent disjunction of broken DNA ends”
A research intelligence initiative by Pepkio
pri.pepkio.com/top-papers/dna-repair-mechanisms/2026/
Topics
DNA double-strand breaks · DSB sites · PARP1 · PARP1 · PARylation · PARylation · PARP1-DNA co-condensation · DNA end synapsis · bottom-up biochemistry reconstitution · PARP1 multimers · Biomolecular condensates · FUS · FUS · DNA end tethering · mechanical forces on DNA · effector protein recruitment · hierarchical DSB condensate assembly · DNA repair · broken DNA end stabilization · PARP1 release from DNA
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Pepkio Research Index (PRI). Topics and Trends in Most Cited DNA Repair Mechanisms Papers, Class of 2026. https://pri.pepkio.com/top-papers/dna-repair-mechanisms/2026. Accessed 2026-07-20. Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459